Warning of magnetic resonance imaging as a study states that injection could cause the formation of mortal material in the body
A chemical injected first Mri scan To help create more sharp images, some patients can induce to experience a potentially fatal complication in rare cases, suggests a new study.
Researchers from the University of New Mexico (UNM) have discovered that gadolinium – a toxic rare earth metal used in the scans of magnetic resonance imaging – could mix with the oxalic acid found in many foods to precipitate tiny nanoparticles of metal in human tissues.
The research, published in the magazine Magnetic resonance imaging, evaluated the formation of these nanoparticles associated with potentially fatal health problems in kidneys and other organs.
Scientists say that Gadolinum -based contrast agents can cause nephrogenic systemic fibrosis, a rare condition that leads to the inspection and induction of the skin, heart and lungs with painful contracture of the joints.
“People gave up after a single dose,” said Brent Wagner, author of the Unw studio.
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When injected, Gadolinum binds strictly to other molecules and is excreted by the body and most people have no adverse effects, researchers say.
However, even in those without symptoms, the metal particles were found in kidney And brain fabrics and was detected in the blood and urine “years after exposure”, scientists say.
The last study has probed because some people get sick while most do not do it and how the gadolinium particles get rid of other molecules in the contrast agent.
“This formation of nanoparticles could explain some things. It could explain why there is such amplification of the disease,” said dr. Wagner.
“When a cell is trying to face this alien metal nanoparticle inside, he will send signals that tell the body to respond,” he said.
Scientists have investigated in particular on the role of oxalic acid, which is found in many foods such as tomatoesSpinach, walnuts and berries – while the molecule binds with metal ions and is implicated in the formation of kidney stones.
Oxalic acid is also formed in the body when people eat food or supplements containing Vitamin CThe researchers say.
They discovered that the oxalic acid caused the precipitate small quantities of gadolinium from the contrasting agent and form nanoparticles that have infiltrated the cells of various organs.
Some patients may be more susceptible to this type of nanoparticles precipitation due to theirs metabolismThe researchers say.
“It could be if they were in a high obseal state or in a state in which the molecules are more prone to connection to gadolinium, leading to the formation of nanoparticles,” said dr. Wagner.
“It could be the reason why some individuals have such terrible symptoms and this massive response to diseases, while other people are fine,” he explained.
The researchers suggest some ways to mitigate the risks associated with MRI scans.
“I would not take vitamin C if I needed a magnetic resonance imaging with contrast due to the reactivity of the metal,” said dr. Wagner.
“I hope we are approaching some tips to help these people,” he added.
